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Reactive Chemicals Hazard Evaluation Workshop

April 13, 2017 @ 9:00 am - 4:00 pm EDT

Reactive Chemicals Hazard Evaluation in Chemical Laboratories, Pilot Plants and Production Facilities

Attention Registered Professional Engineers:

Attendance at this course qualifies for 6 professional development hours. PDH certificates will be provided to interested parties by Mid-Michigan AIChE.


Maintaining control of chemical processes at every scale from laboratory to full production scale is imperative to prevent accidents resulting in serious injury or worse.  By ensuring the process stays within the safe operating zone at all scales, a chemical process can be maintained with minimal down time, and more importantly, the well being of the production workers is ensured with no affect on the surrounding community or damage to the company’s reputation.

This course will introduce students to the general concepts and topics of a so-called Reactive Chemicals Hazard Evaluation.  These include:

  • Thermodynamic and kinetic aspects of chemical processes;
  • Reaction heat calculation and estimation;
  • Calorimetric testing methods;
  • Experimental design based on risk and scale;
  • Energetic materials and functional group identification;
  • Introduction to the CHETAH and CCPS Chemical Reactivity Worksheet software for hazard evaluation;
  • Flammability and dust explosions;
  • Determining worst case scenarios and lines of defense;
  • Temperature of no return (TNR) and time to maximum rate (TMR).

Some special topics are also covered including chemical compatibility and charts.

The formal process of implementing a robust Reactive Chemicals program is also discussed (as implemented in the chemical industry at R&D scale up to full production.  This course will consist of six lectures of one hour each and will include a mixture of formal presentations and interactive discussion.  Although the concepts discussed apply to all scales, the emphasis of the course will be small to moderate scale (lab to pilot plant).

David J. Frurip, Ph.D.
Retired as Technical Leader/Lead EH&S Research Scientist
Reactive Chemicals Discipline
The Dow Chemical Company, Midland MI
Currently:  Frurip Consultancy, LLC and MSU Contractor
Ph: 1-989-631-9308
E-mail: dfrurip@charter.net

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Schedule for the day:


  • An Overview of Process Safety and Reactive Chemicals in the Laboratory and Larger Scales
  • First Steps in RC Hazard Evaluation – Literature Review & Worst Case Scenario Concept
  • Experimental Screening Techniques for Reactive Chemicals

Lunch (on your own)


  • Flammability, Dust Explosions, High Energy Materials, Compatibility
  • Effective Testing Strategies for Reactive Chemicals
  • Estimation of Reaction Heats
  • If time, group discussion of issues brought up by participants


April 13, 2017
9:00 am - 4:00 pm EDT
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MSU St. Andrews Center
1910 W. St. Andrews
Midland, MI 48 United States
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